PCP, commonly known as angel dust, is usually classified as a hallucinogen. However, it also has the effects of a stimulant, an anesthetic, or a narcotic pain-killer, depending on how much is taken.

PCP (phencyclidine) has many of the same effects as LSD, but can be much more dangerous. It has powerful and unpredictable hallucinogenic properties. As a result, individual PCP episodes can vary greatly. Many PCP users are brought to emergency rooms because of its unpleasant psychological effects or because of overdose. Continued PCP use can lead to psychological dependence, as well as tolerance.

PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic. Its use in humans was discontinued in 1965, because patients often became agitated, delusional, and irrational while recovering from its anesthetic effects. PCP is illegally manufactured in laboratories and is sold on the street by such names as angel dust, ozone, wack, and rocket fuel. Killer joints and crystal supergrass are names that refer to PCP combined with marijuana. The variety of street names for PCP reflects its bizarre and volatile effects.

PCP was first tested after World War I as a surgical anesthetic. Because of its adverse side-effects, it was shelved until the 1950s. It was then patented by Parke-Davis and named Sernyl (supposedly referring to serenity), but was again withdrawn from the market because of side effects. It was soon renamed Sernylan, and marketed as a veterinary anesthetic, but again discontinued. Its side effects and long half-life in the human body made it unsuitable for medical applications. It is retained in fatty tissue and is broken down by the human metabolism into PCHP, PPC and PCAA. When smoked, some of it is broken down by heat into 1-phenyl-1-cyclohexene (PC) and piperidine.

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